To treat oxycodone hydrochloride tablets overdose, Main interest needs to be given on the re-institution of the patent airway and establishment of assisted or controlled ventilation.
Acquire this medication specifically as prescribed to reduced the chance of habit. Talk to your health care provider or pharmacist for more facts.
Quickly stopping this medication may well lead to withdrawal, particularly if you have got utilized it for a very long time or in high doses. To avoid withdrawal, your medical professional may possibly decreased your dose slowly and gradually.
Consider sufferers for signs of urinary retention or lowered gastric motility when OXYCONTIN is utilized concomitantly with anticholinergic drugs.
Supportive actions (which includes oxygen and vasopressors) ought to be used from the administration of circulatory shock and pulmonary edema accompanying overdose as indicated. Cardiac arrest or arrhythmias could demand cardiac therapeutic massage or defibrillation.
This is not an entire listing of achievable Unwanted effects. Should you recognize other consequences not shown previously mentioned, Get in touch with your doctor or pharmacist.
Inhabitants pharmacokinetic analyses executed within the clinical research assist The shortage of more info gender effect on the pharmacokinetics of oxycodone from oxycodone hydrochloride tablets.
The dosage is based with your healthcare situation and response to treatment method. Usually do not raise your dose, go ahead and take medication a lot more frequently, or take it for a longer time than prescribed. Adequately cease the medication when so directed.
Consider each tablet with plenty of h2o to make certain complete swallowing promptly right after putting during the mouth [see DOSAGE AND ADMINISTRATION].
If a CYP3A4 inhibitor is discontinued, look at growing the OXYCONTIN dosage till secure drug consequences are attained. Assess for signs of opioid withdrawal.
Oxycodone hydrochloride was genotoxic in oxycodone virkning an in vitro mouse lymphoma assay inside the presence of metabolic activation. There was no evidence of genotoxic probable in an in vitro bacterial reverse mutation assay (Salmonella typhimurium and Escherichia coli) or within an assay for chromosomal aberrations (in vivo mouse bone marrow micronucleus assay).
This medication passes check here into breast milk and can have undesirable outcomes on a nursing toddler. Convey to the medical doctor instantly When your newborn develops unconventional sleepiness, difficulty feeding, or trouble breathing. Speak to your more info medical professional before breastfeeding.
OXYCONTIN must be prescribed only by Health care experts who are proficient about using extended-release/prolonged-performing opioids and how to mitigate the linked threats.
Across specific pharmacokinetic reports, typical plasma oxycodone get more info concentrations for feminine topics had been as many as 25% larger than for male topics on the overall body weight-adjusted basis. The explanation for this difference is mysterious [see Use In Specific Populations].